KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIN28
All Species:
35.76
Human Site:
S120
Identified Species:
65.56
UniProt:
Q9H9Z2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Z2
NP_078950.1
209
22743
S120
G
G
V
F
C
I
G
S
E
R
R
P
K
G
K
Chimpanzee
Pan troglodytes
XP_513232
209
22865
S120
G
G
V
F
C
I
G
S
E
R
R
P
K
G
K
Rhesus Macaque
Macaca mulatta
XP_001114640
143
15918
K65
P
K
G
K
N
M
Q
K
R
R
S
K
G
D
R
Dog
Lupus familis
XP_854985
206
22464
S116
G
G
V
F
C
I
G
S
E
R
R
P
K
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3Y3
209
22701
S120
G
G
V
F
C
I
G
S
E
R
R
P
K
G
K
Rat
Rattus norvegicus
P62961
322
35711
S134
G
G
V
P
V
Q
G
S
K
Y
A
A
D
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506004
274
29355
S130
G
G
S
P
C
L
G
S
E
R
R
P
K
G
K
Chicken
Gallus gallus
Q45KJ5
202
22071
S114
G
G
V
F
C
I
G
S
E
R
R
P
K
S
K
Frog
Xenopus laevis
Q8JHC4
195
21688
S114
G
G
A
P
C
I
G
S
E
R
R
P
K
V
K
Zebra Danio
Brachydanio rerio
Q803L0
202
21867
S114
G
G
A
P
C
V
G
S
E
K
K
P
K
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRN5
195
21575
S112
H
G
G
S
C
Q
G
S
T
Y
R
P
R
I
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P92186
227
25447
L126
G
E
V
E
G
Q
G
L
K
G
S
R
I
H
P
Sea Urchin
Strong. purpuratus
XP_792032
234
25286
S136
D
G
G
D
C
K
G
S
K
R
R
L
R
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
65.5
95.2
N.A.
96.6
20.8
N.A.
53.2
80.8
62.6
66.9
N.A.
34.9
N.A.
26.4
33.7
Protein Similarity:
100
98.5
67.4
96.6
N.A.
98.5
34.4
N.A.
60.2
87
74.1
79.4
N.A.
47.8
N.A.
44
47
P-Site Identity:
100
100
6.6
100
N.A.
100
33.3
N.A.
80
93.3
80
60
N.A.
40
N.A.
20
46.6
P-Site Similarity:
100
100
20
100
N.A.
100
40
N.A.
86.6
93.3
80
80
N.A.
46.6
N.A.
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
0
0
0
0
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
77
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
0
0
0
0
8
8
0
% D
% Glu:
0
8
0
8
0
0
0
0
62
0
0
0
0
0
0
% E
% Phe:
0
0
0
39
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
77
85
24
0
8
0
93
0
0
8
0
0
8
47
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
47
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
8
0
8
0
8
0
8
24
8
8
8
62
0
62
% K
% Leu:
0
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
16
% N
% Pro:
8
0
0
31
0
0
0
0
0
0
0
70
0
8
8
% P
% Gln:
0
0
0
0
0
24
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
70
70
8
16
8
8
% R
% Ser:
0
0
8
8
0
0
0
85
0
0
16
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% T
% Val:
0
0
54
0
8
8
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _